Verified Solution Biology Cell: The Unit of Life

An animal cell is engineering to overexpress a transmembrane protein with a large extracellular domain. Which of the following organelles would likely show an increased workload or activity in this engineered cell?

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Solution ✔ Verified
  • ACytosol for glycolysis.
  • BMitochondria for increased ATP production.
  • CRough Endoplasmic Reticulum and Golgi apparatus.
  • DLysosomes for increased degradation.
Explanation

Transmembrane proteins are synthesized on ribosomes of the Rough Endoplasmic Reticulum (RER) and then processed, folded, and modified in the RER and subsequently transported to the Golgi apparatus for further processing, sorting, and packaging before insertion into the plasma membrane.

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